"Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Circular RNAs (circRNAs)
are a novel class of RNAs, with higher stability and tissue specificity, which may be of value as novel clinical markers."
Oncol Rep. 2020 Aug;44(2):519-532.
piR-13643 and piR-21238 were observed to be significantly upregulated in human PTC. PIWI-interacting RNAs could serve as promising novel biomarkers for accurate detection of PTC.
Aging (Albany NY). 2020 May 19;12(10):9292-9310.
These results imply that the tumour potentially originates from the distal tubule, especially from the cortical collecting duct, and probably retains its cell polarity, except for nuclear inversion. We therefore propose that oncocytic papillary renal neoplasm with inverted nuclei(OPRNIN) is a better name for this tumour type. OPRNIN is a kidney site-specific KRAS mutation neoplasm different from conventional papillary renal cell carcinoma.
Histopathology. 2020 Jun;76(7):1070-1083.
"Sputum is common cytological sample type, but its potential use in EGFR mutation detection in patients with lung cancer is not fully evaluated. An improved sputum cfDNA extraction method was established in this study, and applied super-amplification refractory mutation system (SuperARMS) to detect the EGFR mutation status in sputum cfDNA."
J Mol Diagn. 2020 May 11;S1525-1578(20)30318-4.
"High prevalence of HPV-driven HNSCC (mostly within oropharynx) was detected, with HPV16 type the most
frequent, followed by HPV35 and HPV18. The presence of active HPV infection improved survival of both oropharyngeal and non-oropharyngeal cancer patients and should be taken into account in treatment planning."
J Cancer Res Clin Oncol. 2020 May 5.
The results of clonality analysis showed that the same X chromosome inactivation and consistent mutation states of the IDH1 and IDH2 genes in the two DDCS components. We conclude that the two DDCS components originate from the same primitive cell and that DDCS is monoclonal in origin.
"Journal of Bone Oncology Available online 4 May 2020"